The Substance
TMDB 7.1
HorrorScience Fiction
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
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TMDB 7.1
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
HorrorScience Fiction
Trailers & More
The Substance
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
- Directors
- Coralie Fargeat
- Producers
- Eric Fellner, Coralie Fargeat, Tim Bevan
- Cast and Characters
- Demi Moore (Elisabeth), Margaret Qualley (Sue), Dennis Quaid (Harvey), Edward Hamilton-Clark (Fred), Gore Abrams (Oliver), Oscar Lesage (Troy), Christian Erickson (Man at Diner), Robin Greer (Male Nurse)